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Sunday, 1 April 2012

Info Post
Acquired Immunodeficiency Syndrome or Acquired Immune Deficiency Syndrome (AIDS abbreviated) is a collection of symptoms and infections (or: syndrome) arising out of damage to the human immune system caused by HIV infection, or infection of other viruses that attack similar to other species (SIV, FIV, etc.). own virus is called Human Immunodeficiency Virus (HIV for short) is the virus that weakens the immunity in the human body. People who are exposed to this virus will become susceptible to opportunistic infections or tumor prone. Although there has been handling that can slow the rate of progression of the virus, but this disease can not be cured completely.
HIV and similar viruses are generally transmitted through direct contact between the skin layer (mucous membrane) or the bloodstream with a bodily fluid containing HIV, such as blood, semen, vaginal fluid, preseminal, and breast milk. Transmission can occur through sexual intercourse (vaginal, anal, or oral), blood transfusion, contaminated hypodermic needles, between mother and infant during pregnancy, childbirth, or breastfeeding, as well as other forms of contact with body fluids.


Scientists generally think that AIDS originated from Sub-Saharan Africa. Now, AIDS has become a plague. AIDS has infected an estimated 38.6 million people around the world. On January 2006, UNAIDS in collaboration with the WHO estimate that AIDS has caused the deaths of more than 25 million people since it was first recognized on June 5, 1981. Thus, this disease is one of the deadliest plague in history. AIDS has claimed the cause of death by 2.4 to 3.3 million lives in 2005 alone, and more than 570,000 people of whom are children. [5] A third of these deaths occur in Sub-Saharan Africa, resulting in slow growth economy and destroy the power of human resources there. Antiretroviral treatment can actually reduce the mortality rate and severity of HIV infection, but access to treatment is not available in all countries.
Social penalties for people with HIV / AIDS, are generally more severe when compared with patients with other deadly diseases. Sometimes the social punishment is also tertimpakan to health workers or volunteers, are involved in caring for people living with HIV / AIDS (PLWHA).

    
Cause;
AIDS is the worst form of the result of HIV infection. HIV is a retrovirus that usually attacks the vital organs of the human immune system, such as CD4 + T cells (a type of T cells), makrofaga, and dendritic cells. HIV destroying CD4 + T cells directly and indirectly, whereas CD4 + T cells is required for the immune system to function properly. If HIV killed CD4 + T cells to the number shrank to less than 200 per microliter of blood, the immune cell level will be lost, and the result is a condition called AIDS. Acute HIV infection will progress to clinically latent infection, and symptoms of early HIV infection and ultimately AIDS were identified by examining the number of CD4 + T cells in the blood and the presence of certain infections.
Without antiretroviral therapy, the average duration of progression of HIV infection to AIDS is nine to ten years, and the average survival time after AIDS is only about 9.2 months. However, the rate of progression of the disease in each person varies widely, from two weeks to 20 years. Many factors influence it, such is the strength of the body to defend against HIV (such as immune function) of elderly people who terinfeksi.Orang generally have a weaker immunity than younger people, so more at risk of rapid disease progression. Less access to health care and the presence of other infections such as tuberculosis, can also accelerate the progression of this disease. Genetic heritage of an infected person also plays an important role. Some people are naturally resistant to multiple HIV variants. HIV has some genetic variation and a variety of different forms, which will lead to clinical disease progression is different too. Highly active antiretroviral therapy will be able to extend the average time berkembangannya AIDS, as well as the ability of the average time patients survive.

    
Sexual transmission of
Transmission (transmission) of HIV occurs when there is sexual contact between the vaginal secretions or fluids preseminal someone with rectal, genital, or oral mucous membranes partner. Unprotected receptive sexual intercourse is more risky than unprotected insertive sexual intercourse, anal intercourse and the risk is greater than usual risk of sexual intercourse and oral sex. Oral sex does not mean no risk because HIV can enter through both insertive and receptive oral sex. Sexual violence in general increased risk of HIV transmission is not generally used as a protective and often physical trauma to the vaginal cavity which facilitate HIV transmission.
Sexually transmitted diseases increase the risk of HIV transmission because it can cause the disruption of normal epithelial tissue as a result of genital ulcers, and also because of the accumulation of HIV-infected cells (lymphocytes and makrofaga) in semen and vaginal secretions. Epidemiological studies from Sub-Saharan Africa, Europe and North America indicate that there are approximately four times greater risk of becoming infected with HIV as a result of such genital ulcers caused by syphilis and / or chancroid. Risk is also increased significantly, although smaller, by the presence of sexually transmitted diseases like gonorrhea, chlamydia infection and trichomoniasis which cause local accumulations of lymphocytes and makrofaga.
HIV transmission depends on the infectiousness of people with and susceptibility of the uninfected partner. Infectivity seems to vary at different stages of the disease and are not constant between individuals. Plasma viral load that can not be detected does not necessarily mean that the low viral load in semen or genital secretions. Every 10 times increase in the number of blood plasma HIV RNA equivalent to 81% increase in the rate of HIV transmission. Women are more susceptible to HIV-1 infection due to hormonal changes, vaginal microbial ecology and physiology, and greater vulnerability to sexually transmitted diseases. [38] [39] People who are infected with HIV can still be infected with other viruses are more deadly.

    
Diagnosis
From the date of June 5, 1981, many of which appear to control the definition of the epidemiology of AIDS, such as the definition of Bangui and the World Health Organization definition of AIDS in 1994. However, both systems are in fact aimed at monitoring the epidemic and not for the determination of the patient's clinical stage, because the definitions used are not sensitive or specific. In developing countries, World Health Organization system for HIV infection are used to using clinical and laboratory data, while in developed countries use a classification system Centers for Disease Control (CDC) United States

    
Prevention
Three main lines (routes) the entry of HIV virus into the body is through sexual contact, contiguity (exposure) with body fluids or tissues of infected, and from mother to fetus or baby during the period around birth (perinatal period). Although HIV can be found in saliva, tears and urine of infected people, but there are no records of cases of infection due to these fluids, thus the risk of infection can generally be ignored

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